Prevalence of HIV, hepatitis B/C and syphilis infection among people who inject drugs over the period 2013 – 2025 (data from SPHTDAA Laboratory, Sofia)

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Database (1995-2025).xlsx

Prevalence of HIV infection among people who inject drugs (PWID) over the period 2013 – 2025

	2013	2014	2015	2016	2017	2018	2019	2020	2021	2022	2023	2024	2025
Total number of PWID who were tested	822	661	698	332	319	378	383	254	305	262	203	150	180
Males	607	366	550	240	234	281	272	167	220	192	145	99	133
Females	215	122	148	92	85	97	111	87	85	70	58	49	42
No data												2	5
Number of PWID with a positive test result	28	25	30	10	19	13	49	37	15	38	32	18	33
Males	21	15	24	7	17	12	40	28	14	30	29	17	28
Females	7	1	6	3	2	1	9	9	1	8	3	1	4
No data													1
Proportion positive (%)	3.4%	3.8%	4.3%	3.0%	6.0%	3.4%	12.8%	14.6%	4.9%	14.5%	15.8%	12.0%	18.3%
Males	3.5%	4.1%	4.4%	2.9%	7.3%	4.3%	14.7%	16.8%	6.4%	15.6%	20.0%	17.2%	21.1
Females	3.3%	0.8%	4.1%	3.3%	2.4%	1.0%	8.1%	10.3%	1.2%	11.4%	5.2%	2.0%	9.5
Age <25
Number of PWID who were tested	66	52	86	57		25	14	6	11	16	2	3	4
Number of PWID with a positive test result	4	1	6	1		0	0	0	0	0	0	0	0
Proportion positive (%)	6.1%	1.9%	7.0%	1.8%		0.0%	0.0%	0.0%	0.0%	0.0%	0.0%	0.0%	0.0%
Age 25-34
Number of PWID who were tested	469	228	340	137		80	36	27	53	22	16	18	13
Number of PWID with a positive test result	14	11	12	3		4	13	7	3	3	3	2	0
Proportion positive (%)	3.0%	4.8%	3.5%	2.2		5.0%	36.1%	25.9%	5.7%	13.6%	18.75	11.1%	0.0%
Age > 34
Number of PWID who were tested	287	198	272	138		273	333	221	241	224	185	129	163
Number of PWID with a positive test result	10	4	12	6		9	36	30	12	35	29	16	33
Proportion positive (%)	3.5%	2.0%	4.4%	4.3%		3.3%	10.8%	13.6%	5.0%	15.6%	15.7%	12.4%	20.2

Prevalence of hepatitis B infection among people who inject drugs (PWID) over the period 2013 – 2025

	2013	2014	2015	2016	2017	2018	2019	2020	2021	2022	2023	2024	2025
Total number of PWID who were tested	756	634	698	332	98	359	374	118	259	118	203	150	180
Males	560	350	550	240	71	257	266	82	185	94	144	99	133
Females	196	124	148	92	27	102	108	36	74	24	59	49	42
No data												2	5
Number of PWID with a positive test result	34	38	25	6	5	19	22	9	15	21	30	3	12
Males	27	21	21	6	4	16	18	7	10	17	25	2	10
Females	7	4	4	0	1	3	4	2	5	4	5	1	1
No data													1
Proportion positive (%)	4.5%	6.0%	3.6%	1.8%	5.1%	5.3%	5.9%	7.6%	5.8%	17.8%	14.8%	2.0%	6.7%
Males	4.8%	6.0%	3.8%	2.5%	5.6%	6.2%	6.8%	8.5%	5.4%	18.1%	17.4%	2.0%	7.5%
Females	3.6%	3.2%	2.7%	0.0%	3.7%	2.9%	3.7%	5.6%	6.8%	16.7%	8.5%	2.0%	2.4%
Age <25
Number of PWID who were tested	68	53	86	57	0	24	14	3	11	8	2	3	4
Number of PWID with a positive test result	2	0	1	0	0	0	1	0	1	1	0	0	4
Proportion positive (%)	2.9%	0.0%	1.2%	0.0%	0.0%	0.0%	7.1%	0.0%	9.1%	12.5%	0.0%	0.0%	0.0%
Age 25-34
Number of PWID who were tested	434	225	340	137	20	90	34	15	44	15	16	18	13
Number of PWID with a positive test result	24	10	9	1	2	3	4	2	3	2	4	0	0
Proportion positive (%)	5.5%	4.4%	2.6%	0.7%	10.0%	3.3%	11.8%	13.3%	6.8%	13.3%	25.0%	0.0%	0.0%
Age > 34
Number of PWID who were tested	254	196	272	138	78	245	326	100	204	95	185	129	163
Number of PWID with a positive test result	8	15	15	5	3	16	17	7	11	18	26	3	12
Proportion positive (%)	3.1%	7.7%	5.5%	3.6%	3.8%	6.5%	5.2%	7.0%	5.4%	18.9%	14.1%	2.3%	7.4%

Prevalence of hepatitis C infection among people who inject drugs (PWID) over the period 2013 – 2025

	2013	2014	2015	2016	2017	2018	2019	2020	2021	2022	2023	2024	2025
Total number of PWID who were tested	812	658	698	332	319	368	383	270	302	262	204	150	180
Males	601	367	550	240	234	265	272	175	217	192	145	99	133
Females	211	123	148	92	85	103	111	95	85	70	59	49	42
No data												2	5
Number of PWID with a positive test result	509	439	430	192	245	241	300	187	241	197	175	107	116
Males	381	242	349	159	180	189	229	126	181	150	129	76	88
Females	128	78	81	33	65	52	71	61	60	47	46	30	23
No data												1	5
Proportion positive (%)	62.7%	66.7%	61.6%	57.8%	76.8%	65.5%	78.3%	69.3%	79.8%	75.2%	85.8%	71.3%	64.4%
Males	63.4%	65.9%	63.5%	66.25%	76.9%	71.3%	84.2%	72.0%	83.4%	78.1%	89.0%	76.8%	66.2%
Females	60.7%	63.4%	54.7%	35.9%	76.5%	50.5%	64.0%	64.2%	70.6%	67.1%	78.0%	61.2%	54.8%
Age <25
Number of PWID who were tested	76	50	86	57	12	24	14	6	11	16	2	3	4
Number of PWID with a positive test result	45	19	45	29	5	3	1	0	4	4	0	0	0
Proportion positive (%)	59.2%	38.0%	52.3%	50.9%	41.7%	12.5%	7.2%	0.0%	36.4%	25.0%	0.0%	0.0%	0.0%
Age 25-34
Number of PWID who were tested	207	228	340	137	96	96	36	24	53	22	16	18	13
Number of PWID with a positive test result	173	151	196	81	60	47	35	15	33	11	14	8	5
Proportion positive (%)	83.6%	66.2	57.7%	59.1%	62.5%	49.0%	97.2%	62.5%	62.3%	50.0%	87.5%	44.4%	38.5%
Age > 34
Number of PWID who were tested	287	212	272	138	211	248	333	240	238	224	186	129	163
Number of PWID with a positive test result	207	150	189	82	180	191	264	172	204	182	161	99	111
Proportion positive (%)	72.1%	70.8%	69.5%	59.4%	85.3%	77.0%	79.3%	71.7%	85.7%	81.25%	86.6%	76.7%	68.1%

Prevalence of syphilis infection among people who inject drugs (PWID) over the period 2012 – 2025

	2012	2013	2014	2015	2016	2017	2018	2019	2020	2021	2024	2025
Total number of PWID who were tested	637	777	620	698	332	319	361	369	254	301	149	179
Males	429	551	351	550	240	234	265	350	162	217	99	133
Females	208	226	109	148	92	85	96	19	92	84	48	41
No data											2	5
Number of PWID with a positive test result	71	46	43	28	17	17	12	26	13	23	10	14
Males	29	21	19	14	10	8	8	18	8	16	5	11
Females	42	25	11	14	7	9	4	8	5	7	5	3
Proportion positive (%)	11.1%	5.9%	6.9%	4.0%	5.1%	5.3%	3.3%	7.0%	5.1%	7.6%	6.7%	7.8%
Males	6.8%	3.8%	5.4%	2.5%	4.2%	3.4%	3.0%	5.1%	4.9%	7.4%	5.1%	8.3%
Females	20.2%	11.1%	10.1%	9.5%	7.6%	10.6%	4.2%	42.1%	5.4%	8.3%	10.4%	7.3%
Age <25
Number of PWID who were tested	67	68	55	86	57	12	25	0	7	11	3	3
Number of PWID with a positive test result	3	3	3	2	3	2	0	0	0	0	0	0
Proportion positive (%)	4.5%	4.4%	5.5%	2.3%	5.3%	16.7%	0.0%	0.0%	0.0%	0.0%	0.0%	0.0%
Age 25-34
Number of PWID who were tested	408	448	210	340	137	96	94	9	20	53	18	13
Number of PWID with a positive test result	44	26	15	10	2	13	2	3	1	4	0	0
Proportion positive (%)	10.8%	5.8%	7.1%	2.9%	1.5%	13.5%	2.1%	33.3%	5.0%	7.6%	0.0%	0.0%
Age > 34
Number of PWID who were tested	162	261	195	272	138	211	242	360	227	237	128	163
Number of PWID with a positive test result	24	17	12	16	12	2	10	23	12	19	10	14
Proportion positive (%)	14.8%	6.5%	6.2%	5.9%	8.7%	0.9%	4.1%	6.4%	5.3%	8.0	7.8%	8.6%

Source: State Psychiatric Hospital for Treatment of Drug Addiction and Alcoholism (SPHTDAA), Sofia, NFP, NCPHA